Search results for "Dna viral"

showing 8 items of 8 documents

Saliva: Its value as a biological matrix and current methods of sampling

2006

Saliva is a non-invasive medium, its analysis is useful to measure a wide range of hormones, drugs, narcotics, antibodies, host, microbial, fungal and viral DNA up to salivary mRNA; hence, it has been suggested to be an easy and reliable biomarker in disease diagnostics, such as inflammatory mouth infections/diseases, and in normal health surveillance. In light of this potential, our primary endpoint is to review the current knowledge on saliva analyses and its recent methods of sampling.

0301 basic medicineSalivabiologylcsh:RImmunologylcsh:MedicineSampling (statistics)030206 dentistryDiseaseMatrix (chemical analysis)03 medical and health sciencesBiomarker030104 developmental biology0302 clinical medicinestomatognathic systemImmunologybiology.proteinClinical endpointImmunology and AllergyAntibodyDna viral
researchProduct

Pre-emptive antiviral therapy for active CMV infection in adult allo-SCT patients guided by plasma CMV DNAemia quantitation using a real-time PCR ass…

2013

Pre-emptive antiviral therapy for active CMV infection in adult allo-SCT patients guided by plasma CMV DNAemia quantitation using a real-time PCR assay: clinical experience at a single center

AdultMaleAdolescentPcr assayCongenital cytomegalovirus infectionCytomegalovirusReal-Time Polymerase Chain ReactionSingle CenterHumansMedicineDna viralAgedMonitoring PhysiologicRetrospective StudiesTransplantationbusiness.industryAntiviral therapyvirus diseasesHematologyCmv dnaemiaAllo sctMiddle AgedAllograftsmedicine.diseaseVirologyReal-time polymerase chain reactionHematologic NeoplasmsCytomegalovirus InfectionsDNA ViralImmunologyFemalebusinessStem Cell TransplantationBone Marrow Transplantation
researchProduct

Point Mutation Rate of Bacteriophage ΦX174

2009

Abstract The point mutation rate of phage ΦX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0 × 10−6 substitutions per base per round of copying, which is consistent with Drake's rule (0.003 mutations per genome per round of copying in DNA-based microorganisms).

GeneticsbiologyPoint mutationGenome Viralbiology.organism_classificationmedicine.disease_causeMolecular biologyGenomePhenotypeBacteriophagechemistry.chemical_compoundchemistryNotesDNA ViralEscherichia coliGeneticsmedicinePoint MutationDna viralEscherichia coliBacteriophage phi X 174DNAGenetics
researchProduct

Expression of Pre-S-Encoded Proteins in Sera of Individuals Chronically Infected with Hepatitis D Virus

1988

The sera of 16 individuals chronically infected with the hepatitis D virus were analyzed for hepatitis B virus (HBV) markers. The majority of these patients had a non-replicative form of viral type B hepatitis as indicated by negative tests for HBeAg and HBV-DNA. Pre-S-encoded proteins were detected in 13/16 sera. Sera that were negative for polymerized serum albumin did also not contain pre-S1-encoded proteins. The presence of pre-S-encoded proteins is probably predominantly associated with 22-nm HBsAg forms present in large amounts in sera of individuals with chronic type D hepatitis.

Hepatitis B virusHepatitis b e antigenHepatitis B Surface AntigensvirusesGastroenterologyBiologymedicine.disease_causeHepatitis b surface antigenmedicine.diseaseVirologyHepatitis DHepatitis DViral Envelope ProteinsViral typeChronic DiseaseDNA ViralImmunologymedicineHumansHepatitis B e AntigensViral diseaseHepatitis D virusProtein PrecursorsDna viralDigestion
researchProduct

Comparison of the new Abbott Real Time CMV assay and the Abbott CMV PCR Kit for the quantitation of plasma cytomegalovirus DNAemia

2012

CMV DNA loads measured by the new Abbott RealTime CMV PCR were significantly higher than those quantitated by the Abbott CMV PCR kit (approximately 1 log(10)), and provided a better estimate of the actual CMV load present in plasma specimens as inferred by the use of the WHO standard.

Microbiology (medical)business.industryCongenital cytomegalovirus infectionCytomegalovirusvirus diseasesGeneral Medicinemedicine.diseasePolymerase Chain ReactionVirologylaw.inventionInfectious DiseasesReal-time polymerase chain reactionlawCytomegalovirus InfectionsDNA ViralLinear ModelsmedicineHumansCytomegalovirus infectionsDna viralbusinessPolymerase chain reactionDiagnostic Microbiology and Infectious Disease
researchProduct

Effective stiffening of DNA due to nematic ordering causes DNA molecules packed in phage capsids to preferentially form torus knots.

2012

Observation that DNA molecules in bacteriophage capsids preferentially form torus type of knots provided a sensitive gauge to evaluate various models of DNA arrangement in phage heads. Only models resulting in a preponderance of torus knots could be considered as close to reality. Recent studies revealed that experimentally observed enrichment of torus knots can be qualitatively reproduced in numerical simulations that include a potential inducing nematic arrangement of tightly packed DNA molecules within phage capsids. Here, we investigate what aspects of the nematic arrangement are crucial for inducing formation of torus knots. Our results indicate that the effective stiffening of DNA by …

Models MolecularBacteriophages/genetics; Capsid/chemistry; DNA Viral/chemistry; Models Molecular; Virus AssemblyvirusesBacteriophageQuantitative Biology::Subcellular Processeschemistry.chemical_compoundCapsidstomatognathic systemLiquid crystalStructural BiologyGeneticsMoleculeBacteriophagesDna viralQuantitative Biology::BiomoleculesbiologyVirus Assemblyfood and beveragesTorusbiology.organism_classificationVirologyQuantitative Biology::GenomicsMathematics::Geometric TopologyStiffeningsurgical procedures operativechemistryCapsidDNA ViralBiophysicsDNANucleic acids research
researchProduct

Hepatitis G virus: an old, but newly discovered hepatotropic virus--is it of interest for the nephrologist?

1996

Nephrologymedicine.medical_specialtyTransplantationbiologyHepatitis Viral Humanbusiness.industryFlaviviridaeGastroenterologybiology.organism_classificationVirologyVirusHepatitis GFlaviviridaeLiverNephrologyInternal medicineImmunologyDNA ViralmedicineAnimalsHumansRNA ViralViral diseaseDna viralbusinessNephrology Dialysis Transplantation
researchProduct

Biological activity of 2-phenylethanol and its derivatives

1973

The biosynthesis of herpesvirus DNA in rabbit kidney cells is inhibited to 50% by PEA (2-Phenylethanol) at 0.65 mg PEA/ml. The inhibition of cellular DNA synthesis in uninfected cells by PEA is about twice as sensitive as that of viral DNA synthesis.

medicine.medical_specialtyDNA synthesisfood and beveragesBiological activityGeneral MedicineBiologyVirologyMolecular biologychemistry.chemical_compoundMedical microbiologyBiochemistryBiosynthesischemistryCellular dnaVirologymedicineRabbit kidneyDna viralDNAArchiv f�r die gesamte Virusforschung
researchProduct